Datasheet: Kinase CloneSet

Protein kinases play key roles in most aspects of cellular process, including cell division, signal transduction, apoptosis and cell mobility. Because dysfunction of kinase genes results in a variety of diseases, such as cancer, diabetes and heart disease, this family of genes has captured academic and pharmaceutical research interest. With the completion of the human genome projects, scientists have been able to catalogue the "kinome" - the entire family of kinase genes in human genome. The kinome consists of 518 putative protein kinase genes and represents 1.7% of human gene repertoire.